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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TCF9
All Species:
9.09
Human Site:
S543
Identified Species:
25
UniProt:
P16383
Number Species:
8
Phosphosite Substitution
Charge Score:
0.5
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P16383
NP_003194.3
781
89385
S543
V
E
D
S
K
K
E
S
S
S
D
K
K
V
L
Chimpanzee
Pan troglodytes
XP_001145277
789
90141
S551
V
E
D
S
K
K
E
S
S
S
D
K
K
V
L
Rhesus Macaque
Macaca mulatta
XP_001106597
789
90165
S551
V
E
D
S
K
K
E
S
S
S
D
K
K
I
L
Dog
Lupus familis
XP_540209
782
89720
D544
V
E
D
S
K
K
E
D
N
S
D
K
K
I
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8BKT3
769
87424
D532
M
D
D
I
G
K
E
D
G
S
D
K
K
I
L
Rat
Rattus norvegicus
NP_001128026
729
82818
D492
M
E
D
V
G
K
E
D
G
S
D
K
K
I
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506041
1106
124509
D867
V
S
E
L
R
K
E
D
N
P
D
E
K
I
L
Chicken
Gallus gallus
XP_420072
668
77588
I450
E
K
T
I
L
P
K
I
T
A
F
V
K
N
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786187
854
97624
F592
F
E
D
V
E
E
E
F
C
S
L
P
A
I
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.4
93.2
80.8
N.A.
69.7
66.7
N.A.
43.6
44.5
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
28.5
Protein Similarity:
100
98.3
96
88.8
N.A.
82
76.8
N.A.
55.1
62.7
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
50.9
P-Site Identity:
100
100
93.3
80
N.A.
53.3
60
N.A.
40
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
26.6
P-Site Similarity:
100
100
100
93.3
N.A.
73.3
73.3
N.A.
73.3
40
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
12
0
0
12
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
12
0
0
0
0
0
0
% C
% Asp:
0
12
78
0
0
0
0
45
0
0
78
0
0
0
0
% D
% Glu:
12
67
12
0
12
12
89
0
0
0
0
12
0
0
0
% E
% Phe:
12
0
0
0
0
0
0
12
0
0
12
0
0
0
0
% F
% Gly:
0
0
0
0
23
0
0
0
23
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
23
0
0
0
12
0
0
0
0
0
67
0
% I
% Lys:
0
12
0
0
45
78
12
0
0
0
0
67
89
0
0
% K
% Leu:
0
0
0
12
12
0
0
0
0
0
12
0
0
0
78
% L
% Met:
23
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
23
0
0
0
0
12
0
% N
% Pro:
0
0
0
0
0
12
0
0
0
12
0
12
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
12
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
12
0
45
0
0
0
34
34
78
0
0
0
0
0
% S
% Thr:
0
0
12
0
0
0
0
0
12
0
0
0
0
0
0
% T
% Val:
56
0
0
23
0
0
0
0
0
0
0
12
0
23
23
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _